CBD Suppositories (Endoca)


CBD suppositories for a quick and effective way to take CBD. Suppositories are also ideal if you don’t like swallowing CBD products or have trouble keeping CBD down. Endoca CBD Suppositories are 100% natural and organic, made with pure Hemp Oil and Coconut oil.

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R 1,295.00

R 1,295.00

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10 suppositories

Ingredients: Organic Raw Cannabis Sativa Extract, Coconut oil.


  • 50mg of CBD per suppository (500mg per pack)
  • Made with 100% organic hemp
  • Made with 100% organic coconut oil
  • High bioavailability
  • THC-free


Directions to use: For rectal use or as vaginal capsule. Refrigerate before using. Use good hygiene and wash hands before and after use. Before inserting the CBD suppository, tear the plastic shell lengthwise beginning at the “V” shaped cut at the pointed end of the suppository. Apply a light coating of water to lubricate the CBD suppository before insertion. FOR RECTAL INSERTION: insert suppository past sphincter muscle. Try to wait 15 to 20 minutes before another bowel movement.

Broken CBD suppositories may be reheated in the shells in a sealable, waterproof bag in warm water until melted, then reformed and cooled in a refrigerator. Occasional air bubbles in CBD suppositories are normal and do not indicate a loss of product. FOR VAGINAL INSERTION: CBD Suppository to be inserted high in the vagina. This is best done in a reclined position.


More information:

There are many advantages to the rectal administration of Cannabis compared to the other routes. If the oral route is disallowed due to oral intake restrictions frequently required both before and after surgery, or if the oral route is impaired due to e.g. vomiting, injured jaw or throat, or gastrointestinal difficulties, it is still be possible to administer Cannabis rectally.

CBD cannabis suppositories makes it possible to avoid drug degradation in the gastrointestinal tract and bypass first-pass metabolism in the liver. This allows the cannabinoids to reach the blood in much higher concentrations.

Furthermore, the rectal administration method allows for a greater proportion of CBD to eventually reach the bloodstream. This form for administration offers a much faster uptake than oral administration (approximately 10 minutes, on average). The speed and reliability of CBD suppositories and their uptake combined with their circumvention of many issues surrounding both ingestion and inhalation make rectal applications an excellent addition to both new and pre-existing therapeutic regimens.

With CBD suppositories, initial effects will most often be noticed within 10-15 minutes after application, and these effects will usually last 4-8 hours depending on the physiology and tolerance for cannabis of the individual.

However, there are several issues that can slow the absorption of CBD suppositories from the rectum to the bloodstream. Diarrhea, fecal matter and tumors or cysts on the rectum wall can slow or prevent the cannabinoids from reaching the rectal wall and being absorbed. Rectal dehydration can also drastically reduce the effectiveness of cannabis suppositories. Staying well hydrated by maintaining a healthy consumption of both water and electrolytes may prevent this. However, specific medical condition may also cause rectal dehydration, in which case the solution may not be as simple. In case of concern, medical professionals should be consulted.

CBD suppositories can be used to refine existing therapeutic regimens to greater effects. People, who have been prevented from using cannabis due to inability to administer via ingestion or inhalation, can potentially derive benefit from cannabis for the first time by using cannabis suppositories.


How does CBD work?

Well, many scientists believe that CBD works by interacting with what’s known as the endocannabinoid system. It’s our biological system that’s made up of our body’s vast network of chemical compounds and receptors that act to maintain homeostasis or balance within our body and mind.

Think of it like a dimmer switch – it turns up activity if there isn’t enough or turns down elements if there is an excess.

Does CBD get you high?

It’s a common misconception that CBD gets you high. CBD does not have hallucinogenic or psychoactive effects and so it can’t get you high or produce a euphoric feeling.

That’s the job of another compound, known as THC. While CBD does contain traces of THC, it’s very low (up to 0.3 percent) and so is completely non-psychoactive.

Instead, CBD usage has been shown in studies to have generally benign side effects, low toxicity levels and a whole host of those wonderful potential medicinal benefits that we mentioned earlier.

Potential CBD medicinal benefits:

  • May relieve pain
  • May reduce inflammation
  • May reduce anxiety
  • May help to fight cancer
  • May treat some neurological disorders and seizures
  • May relieve nausea
  • May promote good sleep/ help with insomnia
  • May promote cardiovascular health

CBD and anxiety

One benefit of CBD hemp oil is that it may help in managing anxiety symptoms due to its close relationship with the central nervous system. As research has suggested, CBD hemp oil use could help because it may activate the serotonin 5HT1-A receptor (the ‘feel good’ chemical) found in the cerebral cortex, hippocampus and amygdala — areas in the brain involved in mood and anxiety disorders.

One study found that a 600mg dose of CBD helped those with social anxiety give a speech, while earlier research with animals has shown that CBD can help reduce anxiety by:

Relieving stress - Reducing physiological effects of anxiety, like an increase in heart rate.

Promoting sleep in cases of insomnia

CBD and chronic pain

Because CBD may be able to positively affect your brain’s receptors, regular hemp oil usage may also help with how you manage pain in conditions such as arthritis, inflammatory bowel disease, headaches and fibromyalgia.

That’s because CBD releases neurotransmitters such as dopamine and serotonin that can lessen pain and discomfort while disrupting the activity of pain receptors in the body (scientifically known as the TRPV-1 receptor). In fact, studies sponsored by the National Institutes of Health is looking into how CBD can relieve symptoms caused by:

Muscle pain


Spinal cord injuries

MS pain

CBD and skin conditions

Another one of CBD hemp oil’s uses is that it may help the body with overall inflammation – and so help skin conditions such as acne. Researchers suggest that CBD oil prevents activity in sebaceous glands – a natural oily substance that hydrates the skin. However, too much sebum can lead to acne. More recently, researchers at the University of Colorado have stated that CBD could be a successful alternative, natural product for people to try in treating symptoms related to skin diseases, such as eczema and psoriasis.

CBD and our brains

A potentially surprising health benefit of CBD is that it may be able to protect our brains. This is due to its antioxidant effect. As many neurodegenerative diseases are caused by toxicity in our brains and the accumulation of a neurotransmitter called glutamate, CBD has been found to reduce toxicity levels and lessen neural inflammation (in studies on mice).

CBD and diabetes

One preclinical trial found that CBD lessens the incidence of diabetes from 86% to 30% in diabetic rodents. This is partly due to CBD’s anti-inflammatory properties, which is able to slow down the onset of diabetes.

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CBD Suppositories (Endoca)

CBD Suppositories (Endoca)

CBD suppositories for a quick and effective way to take CBD. Suppositories are also ideal if you don’t like swallowing CBD products or have trouble keeping CBD down. Endoca CBD Suppositories are 100% natural and organic, made with pure Hemp Oil and Coconut oil.

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